Vitamin E Extraordinary
by Ed Blonz, Ph.D.

Vitamin E is emerging as a health superstar What makes vitamin E so interesting is that it poses a challenge to the doctrine that we can get all the nutrients we need solely from a healthful diet. Vitamin E, which before the 1920s was actually thought to be nonessential for humans, has been the subject of hundreds of research studies that point to its ability to help prevent heart disease, cancer, and a host of other disease complications.

Vitamin E's Many Roles
After more than seven decades of research, scientists know that vitamin E plays an important role as an antioxidant, works as an integral part of our immune ,system, and is a key component in the structure of our body's cells.

Vitamin E figures in the cancer equation too. Population studies make a connection between low intake of vitamin E and higher risks for certain cancers, such as those of the prostate and breast. And this important compound doesn't stop there:

The Heart of the Matter
Vitamin E leaped to the headlines a few years ago with two major investigations reported in the New England Journal of Medicine. One study, out of the Channing Laboratory in Boston, looked at information taken from over 80,000 female nurses, ages 34 to 69. The other, at the Department of Epidemiology, Harvard School of Public Health, looked at almost 40,000 male health professionals, ages 40 to 75.

All participants were free of heart disease at the onset. When the volunteers' diets and vitamin supplement intakes were compared with the development of disease, those persons with an intake of at least 100 IUs of vitamin E a day had a 40 percent lower risk for heart disease.

Vitamin E helps more than just your heart - it protects your body against oxygen. This may seem strange since oxygen is essential for life, but it turns out that oxygen has something of a split personality. On the good side, oxygen helps build cells and power the heart. But on the bad side, oxygen has a tendency to form compounds that can contribute to the development of heart disease, cancer, and other degenerative diseases. This is where vitamin E and other antioxidants come into play: They all help keep oxidized fat cells in our body from wreaking havoc on the lining of our arteries.

Supplemental Advice
Key food sources of vitamin E include wheat germ, sunflower seeds, almonds, nuts, and nut and grain oils. Lesser amounts of the vitamin are found in peanuts and vegetables - especially asparagus, kale, spinach, and yams. Vitamin E is also abundant in fortified cereals and whole-grain products.

Can you get all the vitamin E you need from food? In the study reported in the New England Journal of Medicine, the reduction in heart disease risk wasn't evident unless individuals took at least 100 IUs of vitamin E every day. It can be difficult to get that much from food alone, even if your diet is a paragon of nutrition planning.

The United States Department of Agriculture's Recommended Dietary Allowances (RDAs) of 12 to 15 IUs were set up to help eliminate diseases of deficiency. Yet, vitamin E can provide a measure of protection against common ailments and age-related illnesses--a bonus beyond protecting against mere deficiency.

If you're not getting the vitamin E you desire from your diet, you're better to get it from a pill than not at all. A vitamin E supplement won't make a poor diet better, but it can be an important ally to have in the bat-de against heart disease and cancer.

A daily intake of 100 IUs is sug­gested for disease-preventive benefit.

The Safety Question
Although vitamin E's apparent powers are noteworthy, it is not a panacea. Also, vitamin E deficiency is uncommon, occurring predominantly because of malnutrition or rare genetic conditions.

Toxicity from vitamin E is also rare. Subjects in studies who took more than 1,500 IUs a day for extended periods of time reported some gastric upset and nausea, and were at risk for deficiency of vitamins A and K. Also, overdosing on vitamin E can lead to subtle effects on the way blood clots.

One 1994 Finnish study of older males who smoked more than a pack of cigarettes a day for nearly 40 years indicated that vitamin E may slightly increase lung cancer risk, but the results were not conclusive. Also, previous studies revealed that smok­ers show sharply decreased amounts of vitamin E in their system. Unfortunately, details from the Finnish study have been reported out of context over the years creating confusion about vitamin E's value.

Vitamin E's role as a major component in the body's cells and as a member of the immune system's SWAT team helps explain why low levels are associated with increased disease risk. It also supports the evidence that higher intakes decrease the risk for many health problems.

So, should we take vitamin E supplements? Taking 100 to 400 IUs of vitamin E per day in the form of a supplement might not be such a bad idea. Even amounts between 400 to 800 IUs per day are still considered safe, although not recommended. All supplements should be used with caution, as directed, and according to your physician's advice.

Individuals with blood coagulation disorders or those taking anti-coagulation medications should be especially careful with vitamin E supplements. Consult your health professional if you have any health problems or questions.

Ed Blonz is a syndicated columnist and the author of Power Nutrition, published by Signet (1998). Dr. Blonz initially studied nutrition at the University of California, Davis, under DE Harold Olcott, one of the discoverers of vitamin E.

Better Homes and Gardens, February 1999